Lunds universitet

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

Kravprofil

We are seeking a highly motivated postdoctoral scientist to join the SysMic project, Systems microscopy of cancer cell migration, which is a five-year interdisciplinary network project supported by the Swedish Strategic Research Foundation (SSF) program on systems biology.

This project aims at elucidating how cellular signaling and applied forces are coordinated to control cancer cell migration and involves technology development, cell biology, advanced microscopy, image analysis, bioinformatics, multivariate statistics and mathematical modelling. This collaborative project is coordinated by Karolinska Institutet and also includes Uppsala University and Lund University, as well as the biotech companies Sprint Bioscience and Olink Bioscience. As a member of this group, the postdoc will gain access to an established scientific network with state-of-the-art technologies and will regularly interact with PIs, postdocs and graduate students from the member groups.

Description of project and work
This postdoc project will be conducted in the research group of assistant professor Pontus Nordenfelt (nordlab.med.lu.se). Our group is interested in cell biology, microbiology and immunology, with particular emphasis on quantifying molecular mechanisms of host-pathogen interactions, but also including the cell biology of cell migration, cell-cell and cell-matrix interactions and signaling. Much of the research is centred around integrin biology and antibody function. The project will focus on development of integrin-based molecular FRET sensors for use with cell migration studies. Since integrins are involved in so many different types of surface interactions, these sensors can also be applied to other research areas, such as bacterial invasion of human cells.

The successful applicant will participate in an interdisciplinary network project supported by the Swedish Strategic Research Foundation described above. This postdoc project provides opportunities for growth and development as an independent researcher, as there will be possibilities for initiating new research directions, as mentioned above. Selected recent publications: Nordenfelt et al 2017, Nature Communications; Nordenfelt et al 2016, Nature Communications.

Work duties
You will be supervised by assistant professor Pontus Nordenfelt and work together with postdocs, graduate students and senior scientists both within the group and within the SSF-supported network that started in September 2017 and will run for five years. You should be able to work independently, and develop alternative strategies if necessary. You should also be willing to share your knowledge with other group members and be a good team player. The position will likely include supervision of undergraduate degree projects and doctoral students. To increase your chances in a future academic career as well as contribute to the group, you are expected to actively seek external funding under the guidance of the PI.

Qualification requirements
Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier.

Substantial experience in Cell biology; Live cell fluorescence microscopy; Molecular biology; and Quantitative image analysis is required. Experience with FRET, fluorescence polarization, single cell biology and programming (particularly MATLAB or Python) constitute strong merits.

Applicants must possess excellent communication skills and be able to interact and work efficiently in a team. Excellent spoken and written English is required.

Assessment criteria and other qualifications
This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers.

Particular emphasis will be placed on research skills within the subject.

Terms of employment
The employment is a full-time, fixed-term employment of a maximum of 2 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S, OFR/S and SEKO, dated 4 September 2008.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment 2018-04-01
Salary månadslön
Number of positions 1
Working hours 100%
City Lund
County Skåne län
Country Sweden
Reference number PA2017/4229
Contact
  • Pontus Nordenfelt/biträdande universitetslektor, 046-2228571
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
  • SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
Published 08.Jan.2018
Last application date 04.Mar.2018 11:59 PM CET

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