Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

This project aims to develop protocol priming human monocytes towards anti-inflammatory phenotype and to study if their systemic delivery can improve impaired functions in stroke-injured brain of rodents. It will also be addressed whether human monocytes can be converted to cortical neurons through transfection with neurogenic genes in vitro and whether they can differentiate into cortical neurons and promote post-stroke functional recovery after intracerebral delivery.

Work description:

The work will include isolation, characterization and genetic manipulation of human monocytes and their reprogramming to cortical neurons. These cells will then be transplanted in rodent models of stroke. The project involves animal experiments.

Qualifications:

Applicants should have a recent Master degree in molecular and cell biology, neuroscience or closely related disciplines.

The PhD candidate should have basic knowledge and interest in stem cell biology, cell reprogramming, brain inflammation, cellular genetics and restorative/regenerative neurology.

The applicant should also:

-have excellent communication and organization skills

-be fluent in spoken and written English

-have excellent writing and presentation skills

-show flexibility and ability to work in a team environment

 We are looking for highly motivated, flexible, and integrative personalities, capable of working well in multi-national and multi-cultural teams.

Other merits: Previous experience in molecular and cell biology, neuroimmunology, immunocytochemistry and cell culture techniques is favorable. 

Instructions on how to apply: Applications shall be written in English and include a cover letter stating the reasons why you are interested in the position and in what way the research project corresponds to your interests and educational background. The application must also contain a CV, degree certificate or equivalent, and other documents you wish to be considered (grade transcripts, contact information for your references, letters of recommendation, etc.).

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.

Type of employment Temporary position longer than 6 months
First day of employment 2018-09-01 or after agreement
Salary Monthly salary
Number of positions 1
Working hours 100 %
City Lund
County Skåne län
Country Sweden
Reference number PA2018/1030
Contact
  • Zaal Kokaia/Professor, +46 46 222 02 76
  • Emmy Heidenlad/Human Resource Coordinator, +46 46 222 83 47
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
  • SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
  • SEKO: Seko Civil, 046-222 93 66
Published 04.Apr.2018
Last application date 31.May.2018 11:59 PM CET

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